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Saúde / 24/06/2021

HEALTH TECHNOLOGY

Stem Cell Transplant May Help Treat Sclerosis, Study Says

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Stem Cell Transplant May Help Treat Sclerosis, Study Says


Research has shown that stem cell transplants 'reset' our immune system and can treat systemic sclerosis, offering longer life expectancy for operated patients.

The tests were performed on 22 transplant patients at the Hospital das Clínicas de Ribeirão Preto, USP, and evaluated clinical and immunological data all of them.

Now the research will undergo further testing to be certified and implemented as a treatment.

recovered immune system

Stem cell transplantation in more severe cases of systemic sclerosis is nothing new in medicine and has been an option since 2004.

However, there were still gaps, which did not show exactly how much the procedure generated therapeutic response for the patient.

“There were speculations that the transplant could be a stronger immunosuppression and that it would last longer, but what was verified in this research was more than that”, explains the rheumatologist Maria Carolina de Oliveira Rodrigues, researcher at the Cell Therapy Center (CTC) and professor at the Division of Clinical Immunology, Department of Internal Medicine, FMRP.

Dr. Maria concludes, saying that “the transplant altered the immune system in such a profound way, renewing both 'T' and 'B' cells, that it was able to 'reset' the immune system as if the patient were a drink".

more life expectancy

The doctor celebrates the results. She, who has been working for 10 years in monitoring transplant patients, is thrilled by the survey's responses.

Dr. Maria explains that, in general, patients started to have the disease better controlled and gained more time and improved quality of life.

According to the researcher, by knowing how the transplant actually acts on the patients' immune system, it will facilitate treatments in the future.

With this, doctors will be able to better assess the evolution of the disease and use targeted drugs at the time of transplantation so that patients have better outcomes.


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